CDTI is preparing a new edition of the “Science and Innovation Misiones 2026” program, one of the main funding lines for large-scale R&D projects carried out through business collaboration.

The call will be structured into two separate programmes:

  • Science and Innovation Missions (Civil) → with a budget of €45 million
  • Dual Missions (Security and Defence) → with a budget of €100 million

Both lines aim to promote strategic projects aligned with major national challenges, strengthening business competitiveness, strategic autonomy, sustainability, inclusion and equality, and the demographic challenge.

The call is expected to be published in May 2026.


CIVIL MISSIONS

The civil call will focus on seven major strategic areas, which will define funding opportunities:

  • A stable, flexible and resilient energy system
  • Efficient, sustainable and resilient aeronautics
  • Health: multidrug-resistant microorganisms
  • Strategic autonomy in security and defence
  • Women’s health: biomedical research to reduce gender inequalities in this field
  • Food sovereignty in Spain: efficiency, quality, sustainability and food safety
  • Affordable, sustainable and rapidly deployable housing through industrialised and digitalised construction

Below is a summary of the approach and scope of each mission:

1. Stable, flexible and resilient energy system

This mission aims to develop a more resilient, secure and sustainable energy system, with renewable energy playing a key role.

To achieve this, the programme will particularly promote solutions in smart grids and energy storage (chemical, thermal, mechanical or hybrid), which are essential to manage renewable generation, improve grid stability, and strengthen resilience in critical scenarios.

Indicative actions include:

  • Integration of renewables through intelligent, flexible and decentralised systems
  • Development of more efficient, secure and robust decentralised energy systems
  • Improved grid flexibility and demand management
  • Deployment of smart grids for monitoring, control and maintenance
  • Strengthening energy infrastructure security and resilience, including predictive maintenance and climate adaptation
  • Development of large-scale energy storage solutions (including advanced technologies and renewable fuels)

2. Efficient, sustainable and resilient aeronautics

The aviation sector must meet strong global demand while reducing its environmental impact, making decarbonisation a central driver.

The mission seeks to strengthen Spain’s industrial capacity and advance towards more sustainable aviation through technologies in materials, propulsion efficiency, and electrification.

Projects will focus on three main pillars:

  • New materials and designs to reduce weight and improve efficiency
  • Efficient propulsion systems compatible with sustainable aviation fuels (SAF)
  • Electrification and hybridisation of aircraft (more electric aircraft)

3. Health: multidrug-resistant microorganisms

This mission addresses the growing challenge of antimicrobial resistance through a comprehensive One Health approach, covering human, animal and environmental health.

It aims to promote solutions beyond antibiotics, combining capabilities in diagnostics, prevention, innovative therapies and digital technologies to improve detection, treatment and infection control.

Key areas include:

  • Development of new antimicrobials and alternative therapies
  • Rapid diagnostics and advanced health technologies
  • Data-driven surveillance and epidemiological systems
  • Vaccine development and preventive solutions

4. Strategic autonomy in security and defence

This mission seeks to strengthen Spain’s technological sovereignty in security and defence by developing critical, high-R&D capabilities.

It will promote advanced technologies, many of them dual-use, aimed at improving resilience, operational capacity and autonomy in complex environments.

Priority areas include:

  • Medical countermeasures against CBRN threats
  • Advanced guidance, navigation and secure communications systems
  • Digital technologies for tactical cloud environments (AI, data, connected systems)
  • PNT solutions and resilient communications in hostile environments
  • Laser applications in defence and advanced sensing
  • New efficient propulsion systems for autonomous platforms

5. Women’s health: biomedical research to reduce gender inequalities

This mission aims to reduce health inequalities derived from the lack of a gender perspective by promoting research into diseases with higher prevalence or severity in women.

It will support solutions that improve diagnosis, treatment and quality of life, especially in under-researched areas.

Key areas include:

  • Disease prevention and prediction systems
  • Early and specific diagnostic tools
  • Gender-focused treatment development
  • Monitoring and follow-up solutions for medical conditions

6. Food sovereignty in Spain: efficiency, quality, sustainability and food safety

This mission aims to strengthen the strategic autonomy of the agri-food sector, reducing external dependence and improving resilience to climate change.

It will promote technological modernisation and sustainability across the entire value chain, fostering efficient, safe and high-quality production.

Priority areas include:

  • Digitalisation and efficiency improvements (AI, IoT, sensors, traceability)
  • Smart resource management (water, crops, risk prediction)
  • Application of biotechnology across the agri-food chain
  • Circular economy and sustainability solutions
  • Food safety and advanced monitoring and control systems

7. Affordable, sustainable and rapidly delivered housing through industrialised and digital construction

This mission aims to promote new industrialised construction models to increase affordable housing supply, reduce construction times and improve sector sustainability.

It seeks scalable solutions integrating design, manufacturing and execution, strengthening industrial capacity and improving construction efficiency.

Priority areas include:

  • Industrial processes and manufacturing automation
  • Robotics and on-site assistance
  • New sustainable materials and circular economy approaches
  • Solutions to improve resilience to climate risks

DUAL MISSIONS

A specific line of Dual Missions will also be launched, focused on security and defence projects with a higher budget allocation.

This programme aims to strengthen national strategic autonomy by promoting technologies with both civilian and military applications.


If you are interested in submitting a project to the MISSIONS call or want to understand how your company could fit into this opportunity, please do not hesitate to contact us.

Our ASET team will support you throughout the entire process: from evaluating your idea to preparing and submitting the application, ensuring your proposal meets the requirements and maximises its chances of success.

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