Enisa and CaixaBank have held the national final of the 19th edition of the EmprendeXXI Awards, further consolidating these awards as one of the leading benchmarks of the entrepreneurial ecosystem in Spain and Portugal. The ceremony, held on May 27, 2026, in Barcelona, recognized the startups with the greatest potential to address the major challenges of the future.

This year’s awards—jointly organized by Spain’s Ministry of Industry and Tourism through Enisa and CaixaBank through DayOne—focused on innovative solutions that improve people’s lives and promote sustainability. A total of eight awards were presented under the “Challenges of Tomorrow” categories, alongside two special cross-sector awards and a recognition for entrepreneurial achievement.

Eight Startups Leading the Challenges of Tomorrow

The winning companies in the main categories stood out for their innovative approaches in fields such as healthcare, digital transformation, and the ecological transition.

Human & Wellbeing

Health Challenge:

  • Batea Oncology (Galicia), for its innovative device for the treatment of glioblastoma.
  • Finalist: Horus ML.

Generation+ Wellbeing Challenge:

  • Second Hundred (Catalonia), for its solutions aimed at improving the wellbeing and health of the senior population.
  • Finalist: Marisma Biomed.

Education, Culture and Leisure Challenge:

  • Rewoox (Andalusia), specialized in immersive training experiences combining virtual reality and artificial intelligence.
  • Finalist: Foxtery.

Tourism and Travel Challenge:

  • Voltic (Balearic Islands), focused on energy efficiency solutions for the hospitality industry.
  • Finalist: DareMapp.

Business Transformation

Agriculture, Livestock, Fisheries, Forestry and Related Industries Challenge:

  • Veganic (Valencian Community), developer of sustainable biosolutions for agriculture.

Industry 4.0, Manufacturing, Construction and Transport Challenge:

  • Aridditive (Catalonia), promoting sustainable construction through 3D printing technology.
  • Finalist: EXXN Engineering.

Financial Services, Commerce and Business Support Challenge:

  • GPT Advisor (Valencian Community), applying generative AI to financial advisory services.

Living Planet

Living Planet Challenge:

  • ATOM H2 (Catalonia), recognized for its hydrogen-based energy storage solutions.
  • Finalist: S. Lab.

These projects span three major thematic areas—Business Transformation, Human & Wellbeing, and Living Planet—demonstrating the diversity and transformative potential of today’s technology-driven entrepreneurship.

Recognition for Innovation and Social Impact

In addition to the main awards, the jury granted two special distinctions:

  • Polar Nanopharma received the Social Impact Award for developing more effective and less toxic nanomedicine treatments.
  • AjaxDNA was honored with the Disruptive Innovation Award for its technology aimed at accelerating the development of new pharmaceutical therapies.

Meanwhile, the Alumni Achievement Award was presented to Idoven, the e-health startup recognized for its growth and international impact in the field of AI-powered arrhythmia diagnosis.

Financial Support and International Growth Opportunities

Each of the eight category winners received a cash prize of €15,000, while the recipients of the special awards received €9,000 each.

Beyond the financial awards, winners gain access to international acceleration and mentoring programs, including the Moonshot Thinking for Entrepreneurs initiative in Berlin, developed in partnership with ESADE and ICEX.

In addition, all winning companies receive direct approval of the Innovation Assessment required for the Spanish Government’s Emerging Companies Certification, awarded by Enisa.

Nineteen Years Supporting Entrepreneurship

Since its launch in 2007, the EmprendeXXI Awards have supported more than 560 companies through nearly €10 million in prize money and acceleration programs, establishing themselves as a key platform for fostering innovative startups across the Iberian Peninsula.

With this 19th edition, Enisa and CaixaBank DayOne reaffirm their commitment to entrepreneurial talent and to projects capable of delivering real solutions to future economic, social, and environmental challenges.

The recognition granted to this year’s winners highlights the dynamism of an increasingly mature entrepreneurial ecosystem—one capable of generating practical solutions to today’s most pressing challenges. Through initiatives such as EmprendeXXI, innovative talent gains not only visibility but also the tools needed to scale and compete on a global stage.

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